I feel that both the Word of Blake & Comstar lost sight of the Word of Blake as interpreted by Conrad Toyama.
"Comstar" became something of a joke, their leadership made up of Great House plants, their obsession with defeating the Clans, and their eventual devolution from technological & social leader into muscle for the Great Houses. Post-schism Comstar was a dying beast from day one - it had lost it's purpose. It didn't seek to lead the Inner Sphere into a new golden age, it simply sought to crush the Clans and continue making money. It was a soulless corporation devoid of meaning, and a mercenary one at that.
The Word of Blake, on the other hand, let go of all Conrad Toyama preached and turned itself into the very entity Comstar was formed to eliminate and control: An out of control destructive force wiping out the light of mankind. Even in the early days, Comstar had the opportunity to strike out and force the Successor Lords to heel with their technological might, but Conrad Toyama would have none of it. To war with and conquer the Successor States was would make Comstar no better than they, and he choose a higher path, one in which he used Comstar's monopoly on technology & communication to make sure than none challenged The Blessed Order. The Word of Blake threw that all out the window in their panicked efforts to force themselves into a position they felt they owned. They desecrated Blake's dream and made fools and hypocrites of themselves.
Is this the end for Comstar? No. I believe that a true Comstar still exists out there. I beleive that this war between the Word of Blake, "Comstar", and the rest of humanity was little more than the true Comstar cleaning house and enacting their vision. They weeded out the disbelievers, the heretics, & those who paid lip-service and set them upon each other. They distracted the House Lords and other leaders and led them to believe them gone forever. Now, they remain, even deeper behind the scenes, enacting their plan for dominance of the Sphere....