Well, technically, the Doctor being interested in a human is kind of like a human being attracted to a particularly clever Alsatian dog. Rithshathra aside, I don't think the BBC is quite ready "sex outside one's species".
And yes, 9th Doctor's attraction to Rose was, for me, kinda "yuck", and I'll be kind & put it down to post-Time War PTSD. Worth noting the copy left behind with Rose was genetically human.
Counterpoint 4th Doctor's treatment of Leela, vs. Romana. (Although if they meant that at the time, they're better than I give them credit for.)
So let's see.