Guys: no one really stands head and shoulders above the other. That said. John Wayne, Gregory Peck, Sean Connery, Harrison Ford, William Powell(The Thin Man series), Vincent Price, James Coco, David Niven, Peter Sellers, Peter Falk, Fred MacMurry, Ed Norton(The Illusionist)
Girls: I like the chics too much... Claudette Colbert, Audrey Hepburn, Myrna Loy, Jane Seymour, Kelly Hu, Jessica Biel(The Illusionist)... ok my brain baked due to coming up with just those. Though I am sure there are many more that slip my mind.
Not overly impressed with modern actresses and actors.