The trick is to plan your attack to span multiple turns. You spend the thrust to get to the target's general vicinity in one turn, and the next turn you only need to spend a few thrust points to get on the target, sometimeseven being able to simply coast onto it.
Best T-Missile shot I ever saw was launched from halfway across the map in a convention fight. The attacker gave no indication who he was shooting at, as it was a large fight with lots of WarShips, nobody was paying much attention to a Nekohono'o loitering in the backfield. He lined up his shot, and at the end of the missile's movement, he blew almost all of the fuel in a single burn, getting it up to speed 25 or so. Next turn rolls around, and when the time comes, the missile flight zooms across the map right into the hex of a Baron. Didn't have to spend a single thrust point in the actual attack run and the to-hit was practically automatic. Barons do NOT like triple Kraken salvos.