I just got Campaign Ops, too. Whew. Glad I made a coincidental purchase.
So, thanks for the input. I would probably leave it up to the players to decide how large a scope to bring the game. Just some down home raiding and then shooting the breeze at a Periphery watering hole? Or full on grow the Bandit Kingdom. If the Marians and Cricinians (RIP) can do it, why can't we? I'll brainstorm some ideas, though I think either focusing on the former Extractor worlds, or something. Maybe set it late and revive the Ragnarok Union for a third time. Third time's the charm, right?
One thing to consider is how the players are going to be acting as pirates. Are they Robin Hood type where they steal the good stuff from various nobles and leave the serfs/peasants alone? Or are they grabbing whatever is not nailed down, prying up what is, and taking the nails? Or are they going to be adding a few extra Bay Quarters to their Dropship so they can grab slaves and sell them in a market?
If you want a feel-good type of pirate campaign, you might put them near the Draconis Combine or Capellan Confederation where they steal from the nobles that work their peasants almost to death. Make sure to let the players know that if their characters are captured then their characters will be dead in 1-2 months, and the time before that death will NOT be pleasant. Maybe they can pull off a rescue mission (or just assassinating the character so they die quickly)
If you want a steal-everything type of campaign, you might put them near FWL and Lyran alliance, so whatever they steal from the FWL they can sell in Lyran territory, and vice versa (just make sure to use different Dropships/Jumpships so the ruse isn't discovered). Partnering with another pirate unit so both of you can specialize would be a good idea, plus you can trade spares/loot to each other. The fun is that you two will also be eyeing each other for the first sign of backstabbing.
If you want a general slave-taking operation, putting them near the FedSuns, FWL, or Lyrans might be a good idea. Draconis serfs or Cappellan servitors might not notice much of a difference.
If you want a nice mix, you could put them near the DC/Lyran border (or just a short bit coreward), so they can steal from Draconis nobles, rescue peasants/political prisoners, and still steal from Lyran palaces as well.