It'll take a while to try and re-run some numbers I did a decade or more ago, but the biggest change is "no small fusion plants". Whether tokomak, or inertial containment, you need a big installation, with something to get the reaction going (eg. a fission plant). With a sub-based fission reactor (with steam exchangers) coming in with change from 1000 tons, you see what I mean? That's the sparkplug.
I played with this in terms of 'space carriers'. If you can't make a self-contained fusion plant for less than multiples of 1000 tons, then how do you have space fighters (let alone battlemechs - hello, there, Ogres!). My 'solution' was that the fusion engine could be shrunk to 100 tons or so, provided the energy to start it came from external sources (it would be self-sustaining afterwards, barring accident.) So your 'space fighters' (more like space PT boats) got lit up inside the hull of the carrier, and then pushed out before thrusting. BT's magical lasers might well reduce the fusion element to 10s of tons, but you still have to get the energy from somewhere to start the reaction.
Mind you, this is also assuming deut-trit to protium fusion. If you want to stick to canon protium-protium fusion, add one or two zeros to the mass, to account for the layer of catgirls catalysing the reaction.