I would certainly love to see a larger craft, of course. While the Space Shuttle was somethin of a boondoggle, it did serve some functions that are now left unfulfilled.
The ability to carry cargo and crew and grapple with other craft allowed for on-orbit servicing of satellites. Hubble has been refurbished multiple times. That's something that seems important, but cant be done now, though they are looking into automated craft for that.
The other big thing the Space Shuttle did was assemble the ISS. While it's not strictly necessary given other space stations, the Russian Orbital Segment, and even the fact other craft have delivered equipment to the US Orbital Segment (and Axiom has plans to deliver full-sized modules in a few years), I would imagine it could be helpful for early construction stages before all the primary systems are installed and online.
There is Starship which is a heavy lift vehicle that's supposed to be able to carry cargo and crew, though I am not sure how well it will be able to perform the above tasks, but it does at least demonstrate an alternative to a winged craft than can return and be reused (and I would say it's not a space capsule, perhaps even reminds me of the old B space films of yore, landing the rocket on another planet).
In the long term I would LOVE to see the STS plan tried again and actually succeed. That's what the Space shuttle was a part of, and an overall successor that includes all of the components (ground to orbit crew and cargo craft, space tugs and ferries, orbital station all to support larger/longer missions) this time is what would really be good. At the very least the ISS is approaching the end of its lifespan, and the proposed Lunar Gateway is much smaller even if its mission is a bit bolder.
As for capsules, until we're regularly ferrying dozens of people up and down, they still make a lot of sense. Have a small craft when you only need to move a few people and save the costly larger stuff for when you need more.
and yes, magical fusion drives would be great. Though, once in space, NERVA's not bad.