You are a Spheroid or Clan writer working to update the Sherlock Holmes character and write new stories. This new depiction will portray him as a member of one of the Clans living on Strana Mechty circa 3061 (just after the Great Refusal).....
I wanna go back to Strana Mechty angle here
Let's assume that story is adapted by Scorpion Empire media house (gives us option of hindsight) and that it takes place after Great Refusal
Setting: - London was "center of the world" back when novels were written so equivalent would be Katyusha City as the primary location
- Also gives us that historical flavor and nostalgic vibe (like Sherlock Holmes show from the 80s) which would be appreciated by the target audience
Sherlock: - Scorpion freeborn or trueborn Warrior (both are option with Scorpions)
- Ex Seeker for quirkiness and substance habit like OG character
- Recruited by the Watch early in the career, made a name for himself as an investigator
- Transferred to Strana Mechty to work in local Scorpion enclave
- After solving several complicated cases there representatives of other Clans started asking for his assistance with complex or unusual cases, sometimes even off-planet, off the record of course
Watson:- Scientist/doctor like OG character obviously
- Watson in the novels served in the military in Afghanistan where he was wounded and sent home so this Watson would have served as Yeoman on several Seeker parties where he would have been wounded as well
- After recovering he was assigned to Katyusha City as a reward where he works as a doctor
- Lives nextdoor to Sherlock where they meet and start working together
Mycroft: - Sherlock's sibkin/sibling
- Member of the Watch but in much higher rank and specializing in usual spy craft similar to novel character
- Secretive and not always present on Strana Mechty but available for contact via HPG
Lestrade:- Policeman from Katyusha City
- Most likely different Clan or even local neutral official if possible
- One who contacts Sherlock with request for assistance from other Clans
Moriarty: - Mysterious crime mastermind just like OG character, Dark Caste bigwig
- Plot twist could be that he is also member of the Society and his schemes are connected to their plans